Publications

 2024

Ferris J, Lo BP, Barisano G, Brodtmann A, Buetefisch CM, Conforto AB, Donnelly MH, Egorova-Brumley N, Hayward KS, Khlif MS, Revill KP, Zavaliangos-Petropulu A, Boyd LA, Liew S-L. Modulation of the association between corticospinal tract damage and outcome after stroke by white matter hyperintensities. Neurology. Accepted.


Dalton E, Jamwal R, Augoustakis L, Hill E, Johns H, Thijs V, Hayward KS. Prevalence of arm weakness, pre-stroke outcomes and other post-stroke impairments using routinely collected clinical data on an acute stroke unit. Neurorehabilitation and Neural Repair. https://doi.org/10.1177/15459683231223648


Hayward KS, Kwakkel G, Bernhardt J. International Stroke Recovery and Rehabilitation Roundtable Consensus Statements Are Driving Growth and Progress in Our Field. Neurorehabilitation and Neural Repair. 2024. DOI 10.1177/15459683231223648


Hayward KS, Bernhardt J, Kwakkel G. What's on the recovery and rehabilitation horizon: The third international Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke. 2024. https://doi.org/10.1177/17474930231218329


 2023

Rethnam V, Hayward KS, John H, Carvahlo L, Churilov L, Bernhardt J. Clinical and Systems of Care Factors Contributing to Individual Patient Decision-Making for Early Mobilisation Post-Stroke. Frontiers in Stroke. https://doi.org/10.3389/fstro.2023.1293942


Hayward KS, Dalton E, Barth J, Brady M, Cherney LR, Churilov L, Clarkson AN, Dawson J, Dukelow SP, Feys P, Zeiler SR, Lang CE. Control intervention design for preclinical and clinical trials: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable. Neurorehabilitation Neural Repair. https://doi.org/10.1177/15459683231209162


Hayward KS, Dalton E, Barth J, Brady M, Cherney LR, Churilov L, Clarkson AN, Dawson J, Dukelow SP, Feys P, Zeiler SR, Lang CE. Control intervention design for preclinical and clinical trials: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke. https://doi.org/10.1177/17474930231199336


Yap C, Solovyeva O, Rekowski J, Ursino M, Patel D, Dimairo M, Weir C, Chan A-W, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Calvert M, Rantell K, Lee S, Kightley A, Hopewell S, Ashby D, Garrett-Mayer E, Isaacs J, Golub R, Kholmanskikh O, Richards D, Matcham J, Seymour L, Ivy SP, Marshall L, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, de Bono J. Enhancing Reporting Quality and Impact of Early Phase Dose-Finding Clinical Trials: The CONSORT Dose-Finding Extension (CONSORT-DEFINE) Guidance. The BMJ. https://doi.org/10.1136/bmj-2023-076387


Yap C, Solovyeva O, Rekowski J, Ursino M, Patel D, Dimairo M, Weir C, Chan A-W, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Calvert M, Rantell K, Lee S, Kightley A, Hopewell S, Ashby D, Garrett-Mayer E, Isaacs J, Golub R, Kholmanskikh O, Richards D, Matcham J, Seymour L, Ivy SP, Marshall L, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, de Bono J. Enhancing Quality and Impact of Early Phase Dose-Finding Clinical Trial Protocols: The SPIRIT Dose-Finding Extension (SPIRIT-DEFINE) Guidance. The BMJ. https://doi.org/10.1136/bmj-2023-076386


Firth N, Hayward KS, Bernhardt J, Ray R, Barker RN. Stroke survivors’ perspectives on decision-making about rehabilitation and the prospect of taking recovery-promoting drugs: a qualitative study. Exploratory Research in Clinical and Social Pharmacy. https://doi.org/10.1016/j.rcsop.2023.100297


Newton S, Dalton E, Ang H, Klaic M, Thijs V, Hayward KS. Dose, content, and context of usual care in stroke upper limb motor interventions: A systematic review. Clinical Rehabilitation. https://doi.org/10.1177/02692155231172295


Hayward KS, Bernhardt J. Aspiring to restore arm and hand function after stroke. Lancet Neurology. Invited Commentary. DOI: 10.1016/S1474-4422(23)00150-3


Neibling B, Hayward KS, Smith M, Chapman P, Barker RN. Perseverance with home-based upper limb practice after stroke: Perspectives of stroke survivors and their significant others. Disability and Rehabilitation. https://doi.org/10.1080/09638288.2023.2191011 


Bernhardt J, Corbett D, Dukelow S, Savitz S, Solomon J, Stockley R, Sunnerhagen K, Verheyden G, Walker M, Alt Murphy M, Bonkhoff AK, Cadilhac D, Carmichael ST, Dalton E, Dancause N, Edwards J, English C, Godecke E, Hayward KS, Kamalakannan S, Kim J, Kwakkel G, Lang C, Lannin N, Levin M, Lynch E, Mead G, Saa JP, Ward N. The International Stroke Recovery and Rehabilitation Alliance (ISRRA). Lancet Neurology. 2023;22:295-296.  


Liew , Schweighofer, Cole , Zavaliangos-Petropulu, Lo, Han, Hahn, Schmaal, Donnelly, Jeong, Wang, Abdullah, Kim, Hutton, Barisano , Borich, Boyd, Brodtmann, Buetefisch, Byblow, Cassidy, Charalambous, Ciullo, Conforto, Dacosta-Aguayo, DiCarlo, Domin, Dula, Egorova-Brumley, Feng, Geranmayeh, Gregory, Hanlon, Hayward KS, Holguin, Hordacre, Jahanshad, Kautz, Khlif, Kim, Kuceyeski, Lin, Liu, Lotze, MacIntosh, Margetis, Mataro, Mohamed, Olafson, Park, Piras, Revill, Roberts, Robertson, Sanossian, Schambra, Seo,Soekadar, Spalletta, Stinear, Taga, Tang, Thielman, Vecchio, Ward, Westlye, Winstein, Wittenberg, Wolf, Wong, Yu, Cramer, Thompson. Association of brain age, lesion volume, and functional outcome in patients with stroke. Neurology. doi: 10.1212/WNL.0000000000207219


Jeffers MS, Pittman AC, Kendzerska T, Corbett D, Hayward KS, Chen Y. Self-reported sleep disturbances in individuals suffering the effects of stroke: Cross-sectional analysis of Canadian Community Health Survey data from six Canadian provinces and territories. Canadian Medical Association Journal. doi: 10.1503/cmaj.221063

Harvey SR, Rose MR, Brogan E, Pierce JE, Godecke E, Brownsett SLE, Churilov L, Copland D, Dickey MW, Dignam J, Lannin NA, Nickels L, Bernhardt J, Hayward KS.  Examining dose frameworks to improve aphasia rehabilitation research. Archives of Physical Medicine and Rehabilitation. DOI: 10.1016/j.apmr.2022.12.002


 2022

Bernhardt J, Churilov L, Dewey H, Donnan G, English C, Gao L, Hayward KS, Horgan F, Indredavik B, Johns H, Langhorne P, Lindley R, Martins S, Md Ali K, Middleton S, Moodie M, Pandian J, Parsons B, Robinson T, Srikanth V, Thijs V. A Phase III, Multi-Arm Multi-Stage Covariate-Adjusted Response-Adaptive Randomised Trial to Determine Optimal Early Mobility Training after Stroke (AVERT DOSE). International Journal of Stroke. DOI: 10.1177/17474930221142207


Dalton E, Lannin NA, Campbell BCV, Churilov L*, Hayward KS*. Enhancing generalisability of stroke clinical trial results: illustrations from upper limb motor recovery trials. International Journal of Stroke. doi: 10.1177/17474930221135730.*Co-senior authorship. 


Simpson L, Hayward KS, Boyd LA, Larssen B, Mortenson B, Schneeberg A, Silverberg N, Eng J. Responsiveness and trajectory of changes in the Rating of Everyday Arm-use in the Community and Home (REACH) scale over the first-year post-stroke. Clinical Rehabilitation. 2022. DOI: 10.1177/02692155221134413


Wingfield M, Fini N, Williams G, Brodtmann A, Churilov L, Hayward KS. Upper-limb motor intervention elements that drive improvement in biomarkers and clinical measures post-stroke: A systematic review in a systems paradigm. Neurorehabilitation and Neural Repair. 2022;36:726-739.


Hayward KS, Davis A. Science Visualization: Approaches and resources for making communication simple but not simplistic. Stroke (InterSECT). 2002;53:00-00. 


Hayward KS*, Ferris JK*, Lohse KR, Borich MR, Borstad A, Cassidy JM, Cramer SC, Dukelow SP, Findlater SE, Hawe RL, Liew SL, Neva JL, Steward JC, Boyd LA. Observational study of neuroimaging biomarkers of severe upper limb impairment after stroke. Neurology. 2022; 99:e402-e413. *co-first author.


Zavaliangos-Petropulu A …. Hayward KS … Liew SL. Chronic stroke sensorimotor impairment is related to smaller hippocampal volumes: An ENIGMA analysis. Journal of the American Heart Association. 2022;11:e025109. 


Chin LF, Rosbergen I, Hayward KS, Brauer SG. A self-directed upper limb program during early post-stroke rehabilitation: A qualitative study of the perspective of nurses, therapists, and stroke survivors. PLOSOne. 2022 Feb 17(2):e0263413. 


Hayward KS. Critically appraised paper: Intensive motor rehabilitation after stroke is more effective within subacute than acute or chronic phase compared with standard rehabilitation [commentary]. Journal of Physiotherapy. 2022 Apr; 68(2):142.


Neva JL, Greeley B, Chau B, Ferris JK, Jones CB, Denyer R, Hayward KS, Campbell K, Boyd LA. Acute high intensity interval exercise modulates corticospinal excitability in older adults. Medicine & Science in Sports & Exercise. 2022 Apr 1;54(4):673-682.


Dalton EJ, Churilov L, Corbett D, Lannin NA, Campbell BCV, Hayward KS. Early-phase dose articulation trials are underutilized for post-stroke motor recovery: A systematic scoping review. Annals of Physical and Rehabilitation Medicine. 2022;65:101487.


 2021

Hayward KS, Kramer SF, Dalton EJ, Hughes GR, Brodtmann A, Churilov L, Cloud G, Corbett D, Jolliffe L, Kaffenberger T, Rethnam V, Thijs V, Ward N, Lannin NA, Bernhardt J. Timing and dose of upper limb motor intervention after stroke: A systematic review. Stroke. 



Chin LF, Hayward KS, Chai ALM, Brauer SG. A Self-Empowered Upper Limb Repetitive Engagement Program to improve upper limb recovery early post-stroke: Phase II pilot randomized controlled trial. Neurorehabilitation and Neural Repair. 2021 Jul 19;15459683211032967. 



Simpson L, Hayward KS, McPeake M, Field T, Eng JJ. Challenges of estimating accurate prevalence of arm weakness early after stroke. Neurorehabilitation and Neural Repair. 2021 Jul 28;15459683211028240. 



Dalton EJ, Churilov L, Lannin NA, Corbett D, Campbell BCV, Hayward KS. Multidimensional Phase I dose ranging trials for stroke recovery interventions: the key challenges and how to address them. Neurorehabilitation and Neural Repair. 2021 Aug;35(8):663-679.



Ferris J, Neva JN, Vavasour I, Attard K, Greeley B, Hayward KS, Wadden K, MacKay A, Boyd LA. Cortical N-acetylaspartate concentrations are impacted in chronic stroke but do not relate to motor impairment: A MR Spectroscopy study. Human Brain Mapping. 2021 Jul;42(10):3119-3130. OPEN ACCESS.



Bernhardt J, Hayward KS. Where to now? Rehabilitation trialists deliver a well conducted, but neutral, multi-site trial testing self-rehabilitation approaches. Stroke. Invited editorial. 2021 Jun;52(6):1948-1950.



Kennedy C, Bernhardt J, Churilov L, Collier JM, Ellery F, Rethnam V, Carvalho LB, Donnan GA, Hayward KS. Factors associated with time to independent walking recovery post-stroke. Journal of Neurology, Neurosurgery and Psychiatry. 2021;92:402-708. EDITOR'S CHOICE. OPEN ACCESS.



Neibling BA, Jackson SM, Hayward KS, Barker RN. Perseverance with technology-facilitated home-based upper limb practice after stroke: A systematic mixed studies review. Journal of NeuroEngineering and Rehabilitation. OPEN ACCESS.



Rethnam V, Hayward KS, Churilov L, Bernhardt J. The Limitations of Clinical Practice Guidelines to Support Early Mobilisation Decision-Making After Stroke. Frontiers in Neurology (Stroke). OPEN ACCESS.



Hayward KS, Churilov L, Dalton EJ, Brodtmann A, Campbell BCV, Copland D, Dancause N, Godecke E, Hoffman TC, Lannin NA, McDonald MW, Corbett D, Bernhardt J. Advancing stroke recovery through improved articulation of non-pharmacological intervention dose. Stroke. 2021;52:761–769.



Rethnam V, Bernhardt J, Johns H, Hayward KS, Collier JM, Ellery F, Gao L, Moodie M, Dewey H, Donnan GA, & Churilov L. Look closer: The multidimensional patterns of post-stroke burden behind the modified Rankin Scale. International Journal of Stroke. 2021 Jun; 16(4):420-428.  



Chin LF, Hayward KS, Brauer SG. Factors influencing paretic upper limb use during first four-weeks post-stroke: a cross-sectional accelerometry study. American Journal of Physical Medicine & Rehabilitation. 2021 Feb 1;100(2): 153-160.



 2020

Hayward KS, Jolliffe L, Churilov L, Herrmann A, Cloud G, Lannin NA. In search of Kipling's six honest serving men in upper limb rehabilitation: Within participant case-crossover experiment nested within a web-based questionnaire. Disability and Rehabilitation. Disabil Rehabil. 2020 Sep 22;1-9.



Kelly K, Brander F, Strawson A, Ward NS, Hayward KS. Pushing the limits of recovery in chronic stroke survivors: A descriptive qualitative study of user’s perceptions of the Queen Square Upper Limb Neurorehabilitation Programme. BMJ Open. 2020;10:e036481. OPEN ACCESS.


Rethnam V, Langhorne P, Churilov L, Hayward KS, Herisson F, Poletto SR, Tong Y, Bernhardt J. Early Mobilisation Post-Stroke: A Systematic Review and Meta-Analysis of Individual Participant Data. Disability and Rehabilitation. Disabil Rehabil. 2020 Jul 16;1-8.


 Liew SL, Zavaliangos-Petropulu A, Jahanshad N, Lang CE, Hayward KS, Lohse KR, Juliano J, 57 authors, Thompson P. (2020). The ENIGMA Stroke Recovery Working Group: Big data neuroimaging to study brain-behaviour relationships after stroke. Human Brain Mapping, 20 April 2020. OPEN ACCESS.


Chin LF, Hayward KS, Brauer SG. Upper Limb Use Differs Among People With Varied Upper Limb Impairment Levels Early Post-Stroke: A Single-Site, Cross-Sectional, Observational Study. Topics in Stroke Rehabilitation,  2020;27:224-235. 


Hayward KS, Johnson L, Yassi N. Emerging Stroke Clinicians and Scientists: An Australasian Experience. Stroke, 2020;51:e21-e23. OPEN ACCESS.


Borschmann K, Hayward KS. Recovery of upper limb function in the first two years after stroke: A longitudinal, observational study.  Physiotherapy, 2020;107:216-223. OPEN ACCESS.


Chew N, Hayward KS, D’Cruz K, Thompson E, Li X, Lannin NA. Validity and reliability of a smartphone inclinometer app for measuring passive upper limb range of motion in a stroke population. Disability and Rehabilitation. 


Book chapter: Neva JN, Hayward KS, Boyd LA. Therapeutic effects of repetitive transcranial magnetic stimulation (rTMS) in stroke: Moving towards an individualized approach. In Richards, C. S., & Cohen, L. M. (Volume Editors). 2020. The Wiley Encyclopedia of Health. Psychology, Volume III: Clinical Health Psychology & Behavioral Medicine. John Wiley & Sons: Oxford, UK.


 2019

Dalton EJ, Churilov L, Lannin NA, Corbett D, Hayward KS. Dose Articulation in Preclinical and Clinical Stroke Recovery: Refining a Discovery Research Pipeline and Presenting a Scoping Review Protocol. Frontiers in Neurology (Stroke), 2019;10:1148. OPEN ACCESS.


Bernhardt J, Hayward KS, Dancause N, Lannin NA, Ward NS, Nudo R, Farrin A, Churilov L, Boyd LA, Jones TA, Carmichael ST, Corbett D, Cramer SC. A stroke recovery trial development framework: Consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable. 


Chin LF, Hayward KS, Soh AJA Tan CM, Wong CJR, Loh JW, Loke GJH, Brauer SG. An accelerometry and observational study to quantify upper limb use after stroke during inpatient rehabilitation. Physiotherapy Research International, 2019;24:e1784.


Horsley S, Lannin NA, Hayward KS, Herbert R. Additional early active repetitive motor training did not prevent contracture in adults receiving task-specific upper limb training after stroke: a randomised trial. Journal of Physiotherapy, 65, 82-94. OPEN ACCESS.


Wadden K, Peters S, Borich M, Neva JL, Hayward KS, Mang S, Snow NJ, Brown K, Woodward T, Meehan S, Boyd LA. White matter biomarkers associated with motor change in individuals with stroke: A continuous theta burst stimulation study. Neural Plasticity, 2019;7092496. OPEN ACCESS.


Rosbergen IC, Grimley R, Hayward KS, Brauer SG.  The impact of environmental enrichment on timing and nature of patient activities undertaken in an acute stroke unit. Clinical Rehabilitation, 2019 33, 784-795.


Hayward KS, Kramer S, Thijs V, Ratcliffe J, Ward NS, Corbett D, Jolliffe L, Brodtmann A, Cloud G, Kaffenberger T, Bernhardt J, Lannin NA. A systematic review protocol of timing, efficacy and cost effectiveness of upper limb therapy for motor recovery post-stroke. BMC Systematic Reviews, 8, 187. OPEN ACCESS.


Bernhardt J, Borschmann KN, Kwakkel G, Burridge JH, Eng JJ, Walker MF, Bird ML, Cramer SC, Hayward KS, O’Sullivan MJ, Clarkson AN, Corbett D, and the SRRRII Collaboration. Setting the scene for the second Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke, 2019;14:450-456. OPEN ACCESS.


Firth N, Barker RN, Hayward KS, Bernhardt J, Bellingen M, Gunnarsson R. Safety and efficacy of recovery-promoting drugs on motor function after stroke. Journal of Rehabilitation Medicine, 51: 319–330. OPEN ACCESS.

 2018

 2017

Hayward KS, Schmidt JY, Lohse KR, Peters S, Bernhardt J, Lannin NA, Boyd LA. Are we armed with the right data? Pooled individual data review of biomarkers in people with severe upper limb impairment after stroke. NeuroImage Clinical, 2017;13:310-319. OPEN ACCESS.


Rosbergen I, Brauer SG, Grimley R, Fitzhenry S, Hayward KS. Staff perspective of working in an enriched environment embedded in the Acute Stroke Unit: A qualitative process evaluation. BMJOpen, 2017;7:e018226. OPEN ACCESS.


Barker RN, Hayward KS, Carson RG, Lloyd D, Brauer SG. SMART Arm training in subacute stroke survivors with severe arm disability: A randomised controlled trial. Neurorehabilitation and Neural Repair, 2017;31:1005-1016.


Peters S, Wadden KP, Hayward KS, Neva JL, Auriat AA, Boyd LA. A structural motor network correlates with motor function and not impairment post stroke. Neuroscience Letters, 2017;658:155-160.


Hayward KS, Neva JL, Mang CS, Peters S, Wadden KP, Ferris JK, Boyd LA. Interhemispheric pathways are important for motor outcome in individuals with chronic and severe upper limb impairment post stroke. Neural Plasticity, 2017;4281532. OPEN ACCESS.


Hayward KS, Brauer SG, Ruddy KL, Lloyd D, Carson RG. Repetitive reaching training combined with transcranial Random Noise Stimulation in stroke survivors with chronic and severe arm paresis is feasible: A pilot, triple-blind, randomised case series. Journal of NeuroEngineering and Rehabilitation, 2017;14:46. OPEN ACCESS.


Boyd LA, Hayward KS, Ward NS, Stinear CM, Rosso C, Fisher R, Carter A, Leff A, Copland D, Carey L, Cohen L, Maguire J, Basso DM, Cramer SC. (2017). Biomarkers of stroke recovery: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable (SRRR).  OPEN ACCESS.


Rosbergen-Wildemors I, Grimley R, Hayward KS, Walker KC, Rowley D, Campbell AM, McGufficke S, Robertson ST, Trinder J, Janssen H, Brauer SG. Embedding an Enriched Environment in an Acute Stroke Unit increases activity in people with stroke: Results of a pilot study. Clinical Rehabilitation, 2017;31:1516-1528.


Bernhardt J, Hayward KS, Borschmann K, Kwakkel G, Ward NS, Krakauer JW, Wolf SL, Boyd LA, Carmichael ST, Corbett D, Cramer SC. Agreed definitions and a shared vision for new standards in stroke recovery research: The Stroke Recovery and Rehabilitation Roundtable taskforce. 


Lakhani B, Hayward KS, Boyd LA. (2017). Hemispheric asymmetry in myelin after stroke is related to motor impairment and function. NeuroImage Clinical, 2017;14: 344-353.

 2016

 2015

 2014

 2013

 2010